Almotriptan

SKU: orb1306432

Description

Almotriptan (LAS 31416) is a selective 5-HT1B/1D receptor agonist used as a triptan medication for migraine. Its mechanism involves cranial vasoconstriction, which redistributes blood flow by increasing cerebral circulation while reducing extracerebral vessel flow. This pharmacological action has been characterized in both in vitro binding assays and in vivo models of migraine.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 154323-57-6
• MW: 335.46
• Purity: 99.85%
• Formula: C₁₇H₂₅N₃O₂S
• SMILES: CN(C)CCc1c[nH]c2ccc(CS(=O)(=O)N3CCCC3)cc12
• Target: 5-HT Receptor
• Solubility: DMSO:65 mg/mL (193.76 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.96 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5HT Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, Almotriptan, 5-HT Receptor, 5-HT1B/1D, LAS 31416, LAS31416, LAS-31416, Inhibitor, inhibit, Serotonin Receptor

Compound Identifiers

PubChem CID

123606