Alkyltransferase inhibitor 1 hydrochloride

SKU: orb3218230

Description

6-((4-(Aminomethyl)benzyl)oxy)-7H-purin-2-amine hydrochloride belongs to the class of O⁶-benzylguanine DNA repair protein AGT/MGMT inhibitors, and its parent free base (BG-NH₂) is a key amine-terminated building block for SNAP-tag substrate synthesis. Compared to the meta-positional isomer, the inhibitory activity of this para-substituted derivative is only marginally improved over unsubstituted BG.

Key Properties

• CAS Number: 948903-68-2
• MW: 306.75
• Formula: C₁₃H₁₅ClN₆O
• SMILES: Cl.N1=CNC2=C1N=C(N=C2OCC3=CC=C(C=C3)CN)N
• Target: DNA Alkylation

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA Alkylation