ALK5 Inhibitor II (hydrochloride)

SKU: orb1704698

Description

ALK5 Inhibitor II is a potent and selective inhibitor of ALK5 kinase, with IC50 values of 4 nM, 18 nM, and 23 nM in autophosphorylation, cellular TGF-β response, and binding assays, respectively. This compound is a valuable research tool for investigating TGF-β signaling pathways in both in vitro and in vivo models of fibrosis, cancer, and immunology.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2319939-07-4
• MW: 323.8
• Formula: C₁₇H₁₃N₅·HCl
• SMILES: CC1=NC(C2=NNC=C2C3=NC4=CC=CN=C4C=C3)=CC=C1.Cl
• Target: TGF-beta/Smad,Others,ALK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132285158