ALK5-IN-85

SKU: orb3173132

Description

ALK5-IN-85 (Compound 19) is an inhibitor of TGFβRI (ALK5) with an IC50 of less than 100 nM. It can be used for the treatment of respiratory diseases such as idiopathic pulmonary fibrosis, asthma, chronic obstructive pulmonary disease, and lung cancer, as well as for research on skin and ocular fibrotic diseases.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2766583-86-0
• MW: 593.66
• Formula: C₃₃H₃₂FN₇O₃
• SMILES: O=C(OCCN1CCNCC1)C=2C=C(F)C=C(C2)NC(=O)CN3N=C(C=4N=C(C=CC4)C)C(=C3)C=5C=CN=C6C=CC=CC65
• Target: TGF-beta/Smad

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

TGF-beta/Smad