ALK5-IN-34

SKU: orb1687921

Description

ALK5-IN-34 is a potent and selective, orally bioavailable inhibitor of activin receptor-like kinase (ALK5), demonstrating an IC50 of ≤10 nM. It has been utilized in research to investigate TGF-β signaling pathways and has shown efficacy in inhibiting tumor growth in preclinical in vivo models.

Research Area

Cell Biology, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2785430-90-0
• MW: 413.48
• Formula: C₂₃H₂₃N₇O
• SMILES: N(C=1C2=C(N=NC1)C(C)=CC=C2)C3=NC(NC4=CC(=CC=C4)N5CCOCC5)=NC=C3
• Target: Others,TGF-beta/Smad

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163404076