ALK5-IN-33

SKU: orb1687922

Description

ALK5-IN-33 (EX-10) is a potent and selective ALK5 inhibitor with an IC50 of ≤10 nM, demonstrating oral bioavailability. It is a valuable research tool for investigating TGF-β signaling in fibrotic diseases and cancer, with utility in both cellular and animal models.

Research Area

Cell Biology, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2785430-89-7
• MW: 413.48
• Formula: C₂₃H₂₃N₇O
• SMILES: N(C=1C2=C(N=NC1)C(C)=CC=C2)C3=NC(NC4=CC=C(C=C4)N5CCOCC5)=NC=C3
• Target: TGF-beta/Smad,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163404110