ALK inhibitor 1

SKU: orb1310010

Description

ALK inhibitor 1 is a potent and selective small molecule targeting the anaplastic lymphoma kinase. It is widely utilized in biochemical and cellular assays to investigate ALK-driven oncogenesis and has been employed in preclinical in vitro and in vivo cancer research models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 761436-81-1
• MW: 562.48
• Purity: 98.55% (May vary between batches)
• Formula: C₂₃H₂₈BrN₇O₃S
• SMILES: CNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCN(C)CC2)ncc1Br
• Target: IGF-1R,ALK,FAK
• Solubility: H2O:0.1 mg/mL (0.18 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.87 mM);DMSO:90 mg/mL (160.01 mM)

Bioactivity

• Target IC50:
  IGF-1R: 90 nM
• In Vitro:
  ALK inhibitor 1 inhibits IGF-1R.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

serine/threonine, testis-specific, TSSK2, reversible, PTK2, PTK2 protein tyrosine kinase 2, adhesion, ALK tyrosine kinase receptor, ALK inhibitor 1, ALK inhibitor1, ALK inhibitor-1, ALK, Anaplastic lymphoma kinase, Anaplastic lymphoma kinase (ALK), contraception, CD246, Cluster of differentiation 246, inhibit, kinase, male, Inhibitor, IGF1R, IGF-1R, FAK, Focal adhesion kinase, focal

Compound Identifiers

PubChem CID

24857689