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ALK-IN-24

SKU: orb3210986

Description

ALK-IN-24 is an orally active ALK inhibitor with an IC50 value of 1.7 nM. It also inhibits the insulin receptor kinase, with an IC50 value of 6 nM. ALK-IN-24 suppresses the proliferation of lung adenocarcinoma cells and hinders ALK-driven tumor growth in xenograft mouse models. It is applicable for research related to non-small cell lung cancer.

Images & Validation

Key Properties

CAS Number2093414-37-8
MW556.08
FormulaC26H30ClN7O3S
SMILESO=S(=O)(C=1C=CC=CC1NC2=NC(=NC=C2Cl)NC=3C=C4C(=CC3OC)N5C(=NN(C)CC5)CC4)C(C)C
TargetIGF-1R,ALK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information