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ALG-001075

SKU: orb3135845

Description

ALG-001075, a capsid assembly modulator (CAM), is an orally active inhibitor of HBV. It effectively suppresses HBV DNA production in primary human hepatocytes and significantly reduces extracellular levels of HBsAg/HBeAg and intracellular HBV RNA. In AAV-HBV mouse models, ALG-001075 notably decreases HBV DNA levels. It can be utilized in research related to chronic hepatitis B (CHB).

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number2495324-66-6
MW422.41
FormulaC22H19FN4O4
SMILESN#CC1=CC(=CC=C1F)NC(=O)C2=C(C(C(=O)C(=O)NC3(C#C)COC3)=C(N2C)C)C
TargetHBV

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information