[Ala1,3,11,15]-Endothelin

SKU: orb1679253

Description

This compound is a potent and selective endothelin receptor type B (ETB) agonist, exhibiting high affinity for the ETB receptor (IC50 = 0.33 nM) with over 6600-fold selectivity versus the ETA receptor. It is a valuable pharmacological tool for studying ETB-mediated vasodilation, cell proliferation, and endothelin system function in cardiovascular and pulmonary research models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Endothelin Receptor
• CAS Number: 121204-87-3
• MW: 2368
• Formula: C₁₀₉H₁₆₃N₂₅O₃₂S
• SMILES: C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CC=C(O)C=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](C)N)=O)CO)=O)C)=O)CO)=O)CO)=O)CC(C)C)=O)CCSC)=O)CC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)C)=O)C(C)C)=O)=O)=O)C)=O)=O)CC(C)C)=O)CC(O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C(O)=O)C=4C=5C(NC4)=CC=CC5

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16143287