[Ala11,D-Leu15]-Orexin B acetate

SKU: orb1679374

Description

[Ala11,D-Leu15]-Orexin B acetate is a potent and selective orexin-2 receptor (OX2R) agonist, exhibiting an EC50 of 0.13 nM with 400-fold selectivity versus OX1R. This tool compound is valuable for investigating OX2R-specific signaling in vitro and its role in sleep/wake regulation and neuroendocrine functions in vivo.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: OX Receptor
• Molecular Weight: 2917.31
• Purity: 98.18% (May vary between batches)
• Formula: C₁₂₂H₂₁₀N₄₄O₃₇S
• SMILES: CC(O)=O.CSCC[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C)NC([C@H](C)NC([C@H](CC1=CNC=N1)NC([C@H](CC(N)=O)NC(CNC([C@H](CO)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H]2N(C([C@H]3N(C(CNC([C@H](CO)NC([C@H](CCCNC(N)=N)N)=O)=O)=O)CCC3)=O)CCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Storage & Handling

• Storage: store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

[Ala11,D Leu15] Orexin B acetate, [Ala11,DLeu15]Orexin B acetate, [Ala11,D-Leu15]-Orexin B Acetate, [Ala11,D-Leu15]-Orexin B acetate (532932-99-3 Free base), 532932-99-3, 532932-99-3 Free base, OXReceptor, OX Receptor, OX2

Compound Identifiers

PubChem CID

168013641