AKT1-IN-11

SKU: orb3174190

Description

AKT1-IN-11, a derivative of Podophyllotoxin, functions as a dual inhibitor of AKT1 and tubulin. It reduces phosphorylation levels of AKT kinase in tumor cells, disrupts cell proliferation, causes G2/M phase arrest, and induces apoptosis. Additionally, AKT1-IN-11 promotes tubulin depolymerization and is applicable in colorectal cancer research.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3087064-94-3
• MW: 692.7
• Formula: C₃₃H₃₂N₄O₁₁S
• SMILES: O=C1[C@@]2([C@@H](C=3C([C@H](OCC4=CN(S(=O)(=O)C5=CC=C(NC(C)=O)C=C5)N=N4)[C@]2(CO1)[H])=CC6=C(C3)OCO6)C7=CC(OC)=C(OC)C(OC)=C7)[H]
• Target: Microtubule Associated,Apoptosis,Akt

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Microtubule Associated,Apoptosis,Akt