AKT-IN-6

SKU: orb1693853

Description

AKT-IN-6 (INCB-047775) is a selective small molecule inhibitor of Akt, a key kinase in growth factor and cytokine signaling pathways. Its application in research includes investigating the role of aberrant Akt signaling in cancer and metabolic disorders, utilizing both in vitro cellular assays and in vivo preclinical models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1430056-54-4
• MW: 389.43
• Purity: 98.83% (May vary between batches)
• Formula: C₂₂H₂₀FN₅O
• SMILES: Cn1ncc(C#N)c1-c1ccc2C(=O)N(Cc2c1)[C@H](CN)Cc1cccc(F)c1
• Target: Akt
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.27 mM);DMSO:112.5 mg/mL (288.88 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

INCB047775, INCB-047775, INCB 047775, Akt, AKT-IN-6

Compound Identifiers

PubChem CID

89499684