AKT-IN-3

SKU: orb1710465

Description

AKT-IN-3 is a potent, orally bioavailable pan-Akt inhibitor with low hERG liability, demonstrating low nanomolar IC50 values against Akt1/2/3. It also inhibits several other AGC kinases, including PKA and PKC. This profile supports its use in cancer research for investigating PI3K/Akt pathway signaling in both cellular and animal models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2374740-21-1
• MW: 526.36
• Formula: C₂₃H₂₃Cl₂F₂N₅O₃
• SMILES: CNC(=O)C[C@@H]1C[C@H]([C@@H](CN1)NC(=O)c1cc(c(Cl)o1)-c1c(Cl)cnn1C)c1ccc(F)c(F)c1
• Target: Akt,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138911338