AKR1C3-IN-15

SKU: orb3028031

Description

AKR1C3-IN-15 (compound 30) is an effective and selective AKR1C3 inhibitor with an IC50 value of 5 nM. It enhances Sorafenib-induced ROS production, promotes apoptosis, and restores sensitivity to Sorafenib in hepatocellular carcinoma (HCC) models, as demonstrated in both in vitro and in vivo studies.

Key Properties

• CAS Number: 3059671-44-9
• MW: 341.33
• Formula: C₁₉H₁₆FNO₄
• SMILES: O=C(O)C1=CC=C(C=C1)CN(C(=O)C2=CC=3C=CC(F)=CC3OC2)C
• Target: Apoptosis,Reductase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,Reductase