AKN-028 acetate

SKU: orb1688679

Description

AKN-028 acetate is a potent and orally bioavailable FLT3 tyrosine kinase inhibitor (IC₅₀ = 6 nM) that blocks autophosphorylation. It demonstrates dose-dependent cytotoxicity and induces caspase-3-mediated apoptosis in vitro, supporting its research application in models of acute myeloid leukemia (AML).

Research Area

Cardiovascular Research, Cell Biology, Protein Biochemistry, Signal Transduction

Key Properties

• MW: 362.39
• Formula: C₁₉H₁₈N₆O₂
• Target: FLT,Apoptosis,Others,Caspase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

FLT,Apoptosis,Others,Caspase