AICAR

SKU: orb1225477

Description

AICAR (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes; inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes at 0.5 mM, inhibits insulin-stimulated glucose and reduces GLUT4 translocation in 3T3-L1 adipocytes; down-regulates the insulin receptor expression in HepG2 cells.

Key Properties

• CAS Number: 2627-69-2
• MW: 258.2
• Purity: >98% (HPLC)
• Formula: C₉H₁₄N₄O₅
• SMILES: O=C(C1=C(N)N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C=N1)N
• Target: AMPK
• Solubility: DMSO: ≥ 30 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Acadesine | AICA Riboside

Quick Database Links

Gene Symbol

AMPK