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AHR antagonist 5 hemimaleate

SKU: orb1686654

Description

AHR antagonist 5 hemimaleate is a potent, orally bioavailable aryl hydrocarbon receptor (AHR) inhibitor with an IC50 below 0.5 µM. It demonstrates synergistic antitumor activity in combination with anti-PD-1 therapy in preclinical models, making it a valuable tool for immuno-oncology and cancer metabolism research.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW499.55
FormulaC29H28FN7O4
TargetOthers,Aryl Hydrocarbon Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information