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AHR antagonist 2

SKU: orb1710470

Description

AHR Antagonist 2 is a potent and selective small molecule inhibitor of the aryl hydrocarbon receptor, exhibiting IC₅₀ values of 0.885 nM for human AHR and 2.03 nM for mouse AHR. This research compound is widely utilized in vitro and in vivo to investigate AHR-mediated pathways in immunology, toxicology, and oncology.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2338747-54-7
MW418.37
Purity99.38% (May vary between batches)
FormulaC20H17F3N4O3
SMILESC[C@@H](CO)NC(=O)c1cc(nc(n1)-c1cccnc1)-c1ccc(OC(F)(F)F)cc1
TargetAryl Hydrocarbon Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.95 mM);DMSO:225 mg/mL (537.8 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AHR antagonist 2, Aryl Hydrocarbon Receptor, aryl hydrocarbon receptor, ArylHydrocarbonReceptor

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Key Properties

No computed properties available.

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Protocol Information

AHR antagonist 2 (orb1710470)

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% DMSO +
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% Tween 80 +
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Available Sizes

Select a size below

500 mg
1 mg
$ 90.00
5 mg
$ 160.00
1 ml x 10 mM (in DMSO)
$ 180.00
10 mg
$ 240.00
25 mg
$ 380.00
50 mg
$ 520.00
100 mg
$ 720.00