AGI-43192

SKU: orb1685235

Description

AGI-43192 is a brain-penetrant, potent inhibitor of methionine adenosyltransferase 2A (MAT2A), blocking S-adenosylmethionine (SAM) production. This tool compound enables research into SAM-dependent processes in the central nervous system and is investigated in oncology for its potential anti-cancer effects in preclinical models.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2377491-54-6
• MW: 484.86
• Purity: 99.89%
• Formula: C₂₃H₁₆ClF₃N₆O
• SMILES: Cn1cc2cc(ccc2n1)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O
• Target: Others,Methionine Adenosyltransferase (MAT),Somatostatin
• Solubility: DMSO:45 mg/mL (92.81 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:8 mg/mL (16.5 mM)

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AGI 43192, AGI43192, AGI-43192, MAT2A

Compound Identifiers

PubChem CID

139551841