Agerafenib hydrochloride

SKU: orb1707470

Description

Agerafenib hydrochloride is a potent and selective BRAFV600E inhibitor with a dissociation constant (Kd) of 14 nM. It is a valuable research tool for investigating oncogenic BRAF signaling in both cellular assays and in vivo models of melanoma and other cancers.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1227678-26-3
• MW: 553.92
• Formula: C₂₄H₂₃ClF₃N₅O₅
• SMILES: Cl.COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C(F)(F)F)c3)c2cc1OC
• Target: c-RET,c-Kit,Raf

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

56954675