AG957

SKU: orb1306201

Description

Tyrphostin AG957 is a BCR-ABL tyrosine kinase inhibitor that reinstates functional beta1 integrin adhesion and signaling in CML progenitors. It is used in research on leukemia cell adhesion, migration, and signaling pathways in both in vitro and ex vivo experimental models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 140674-76-6
• MW: 273.28
• Purity: 99.27% (May vary between batches)
• Formula: C₁₅H₁₅NO₄
• SMILES: COC(=O)c1ccc(NCc2cc(O)ccc2O)cc1
• Target: Bcr-Abl
• Solubility: DMSO:60 mg/mL (219.56 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.32 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

myelogenous, lipopolysaccharide, kinase, inhibit, NSC 654705, paxillin, NSC654705, NSC-654705, leukemia, Inhibitor, integrins, hematopoiesis, BCR/ABL, BcrAbl, Bcr-Abl, c-Abl, AG 957, AG957, AG-957, cytoskeleton, Chronic, Tyrphostin AG 957, Tyrphostin AG957, Tyrphostin AG-957, tyrosine

Compound Identifiers

PubChem CID

2064