AG-370

SKU: orb1704967

Description

AG 370 is an indole tyrphostin compound that potently inhibits PDGF-induced mitogenesis with an IC50 of 20 µM, while showing only weak activity against the EGF receptor. This selective inhibitor is a valuable research tool for studying PDGF signaling pathways in cellular proliferation assays and related in vitro research models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 134036-53-6
• MW: 259.27
• Formula: C₁₅H₉N₅
• SMILES: C(=C(C(=C(C#N)C#N)N)C#N)C=1C=C2C(=CC1)NC=C2
• Target: Others,PDGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

2042