Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

AG-205

SKU: orb1737667

Description

(rac)-AG-205 is a potent small molecule inhibitor of progesterone receptor membrane component 1 (PGRMC1). It suppresses sterol synthesis-related genes like INSIG1 and demonstrates neuroprotective potential in research by inhibiting NF-κB and BDNF/PI3K/AKT pathways in models of hypoxic-ischemic injury.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number442656-02-2
MW454.98
FormulaC22H23ClN6OS
SMILESCN1CC[C@@H]2[C@H](C1)c1cc(C)ccc1N2C(=O)CSc1nnnn1-c1ccc(Cl)cc1
TargetNF-κB,Others,Akt

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • (4R,9S)-AG 205 [orb1738645]

    1375078-57-1

    454.98

    C22H23ClN6OS

    50 mg, 100 mg, 25 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

AG-205 (orb1737667)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%