AG-1557 hydrochloride (189290-58-2(free base))

SKU: orb1302645

Description

AG-1557 is a potent small molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, with a pIC50 of 8.194. It is a valuable research tool for studying EGFR-driven signaling pathways in both in vitro cellular assays and in vivo cancer models.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• Target: EGFR,Potassium Channel
• Molecular Weight: 443.66
• Purity: 98.95%
• Formula: C₁₆H₁₅ClIN₃O₂
• SMILES: Cl.COc1cc2ncnc(Nc3cccc(I)c3)c2cc1OC

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AG 1557 hydrochloride (189290 58 2(free base)), AG1557 hydrochloride (189290582(free base)), AG-1557 hydrochloride (189290-58-2(free base)), EGFR, hERG

Compound Identifiers

PubChem CID

11316711