AG-13958 monohydrochloride

• Catalog Number: orb1740028
• Category: Small Molecules
• Description: AG-13958 monohydrochloride
• Purity: 98.00%
• MW: 503.96
• Biological Activity: AG-13958 monohydrochloride is the HCl salt of AG-13958 --- a VEGFA inhibitor potentially for the treatment of age-related macular degeneration. Neovascular AMD, a subtype characterized by the growth of new, pathologic blood vessels, results in most of the cases of severe and rapid vision loss associated with AMD. A critical activator of angiogenesis in neovascular AMD is VEGF.
• CAS Number: 319463-49-5
• Formula: C₂₆H₂₃ClFN₇O
• SMILES: C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(NC4=CC(NC(=O)C=5N(C)N=C(C)C5)=C(F)C=C4)=CC3)NN2.Cl
• Storage: -20°C
• Note: For research use only