AG-09/1

SKU: orb1690584

Description

AG-09/1 is a potent and selective agonist of the formyl peptide receptor 1 (FPR1), specifically inducing chemotaxis in human neutrophils. This small molecule is a valuable research tool for studying innate immune responses, inflammation, and neutrophil migration in both in vitro and in vivo experimental models.

Key Properties

• CAS Number: 356776-32-4
• MW: 358.37
• Purity: 99.59%
• Formula: C₁₆H₁₄N₄O₄S
• SMILES: COc1ccc2nc(SCC(=O)Nc3ccc(cc3)[N+]([O-])=O)[nH]c2c1
• Target: Others
• Solubility: DMSO:100 mg/mL (279.04 mM)

Bioactivity

• In Vitro:
  N-formyl peptides stimulate phagocyte activation via G protein-coupled receptors, specifically through the formyl peptide receptor (FPR) family. Among them, FPR1, the initially cloned member, encodes a receptor with high affinity for N-formyl-methionyl-leucyl-phenylalanine (fMLF).

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FPR1, AG09/1, AG-09/1, AG 09/1

Compound Identifiers

PubChem CID

3901842