Afamelanotide acetate

SKU: orb1299681

Description

Afamelanotide acetate is a synthetic analog of α-MSH and a first-in-class agonist of the melanocortin-1 receptor. It is used in research for Erythropoietic Protoporphyria (EPP), with studies exploring its photoprotective effects in both in vivo models and in vitro receptor activation assays.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1566590-77-9
• MW: 1706.9
• Purity: 99.49% (May vary between batches)
• Formula: C₈₀H₁₁₅N₂₁O₂₁
• SMILES: CC(O)=O.CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
• Target: Melanocortin Receptor
• Solubility: DMSO:22.5 mg/mL (13.18 mM);H2O:25 mg/mL (14.65 mM)

Storage & Handling

• Storage: keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

skin cancers, α-MSH, MT-I, MC1R, melanotropic peptide, Melanotan, MelanocortinReceptor, Melanocortin Receptor, melanocortin-1 receptor, Melanotan I

Compound Identifiers

PubChem CID

131839615