AF-2112

SKU: orb2277951

Description

AF-2112 is a flufenamic acid-derived TEAD inhibitor that potently reduces the expression of downstream targets CTGF, Cyr61, Axl, and NF2. This small molecule is a valuable research tool for investigating Hippo signaling pathway biology in both cellular and animal models of cancer and fibrosis.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2996821-62-4
• MW: 351.37
• Formula: C₂₁H₁₈FNO₃
• SMILES: C1=CC=C(C=C1)CCOC2=CC=CC(=C2)NC3=C(C=CC(=C3)F)C(=O)O
• Target: YAP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

YAP