AEG40826

SKU: orb1741219

Description

AEG40826 (HGS1029) is a small-molecule IAP inhibitor that antagonizes IAP proteins to restore caspase-mediated apoptosis, potentially overcoming chemoresistance. It is applied in oncology research, demonstrating synergistic antitumor activity with cytotoxic agents in both in vitro and in vivo cancer models.

Key Properties

• CAS Number: 949963-04-6
• MW: 1045.32
• Formula: C₅₈H₈₀N₁₀O₈
• SMILES: C([C@@H](NC([C@@H](NC)C)=O)[C@@](C)(C)C)(=O)N1[C@H](C(N[C@H]2C=3C(CCC2)=CC=CC3)=O)C[C@H](NC(=O)C4=CC=C(C(N[C@@H]5CN(C([C@@H](NC([C@@H](NC)C)=O)C(C)(C)C)=O)[C@H](C(N[C@H]6C=7C(CCC6)=CC=CC7)=O)C5)=O)C=C4)C1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16738866