AE-848/42025892 2HCl

SKU: orb3218075

Description

AE-848/42025892 2HCl is a small molecule that selectively induces apoptosis in multiple myeloma (MM) cells while sparing normal peripheral blood mononuclear cells, inhibiting U266 and RPMI8226 cell viability in a dose- and time-dependent manner, AE-848/42025892 2HCl induces the cleavage of caspase-8, caspase-3, and poly ADP-ribose polymerase (PARP), resulting in loss of mitochondrial membrane potential (MMP).thereby providing a therapeutic window for MM treatment.

Key Properties

• MW: 633.61
• Purity: 100.00% (May vary between batches)
• Formula: C₃₄H₃₈Cl₂N₆O₂
• SMILES: N=C1N(CCOCCOCCN2C(C=CC=C3)=C3N(CC4=CC=CC=C4)C2=N)C5=CC=CC=C5N1CC6=CC=CC=C6.Cl.Cl
• Target: Caspase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase