Adrenic Acid

SKU: orb1307112

Description

Adrenic acid (cis-7,10,13,16-docosatetraenoic acid) is a very-long-chain polyunsaturated fatty acid present in human blood and myelin. It serves as a research tool for studying lipid metabolism, neurobiology, and peroxisomal disorders in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 28874-58-0
• MW: 332.52
• Formula: C₂₂H₃₆O₂
• SMILES: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O
• Target: Endogenous Metabolite
• Solubility: DMSO:260 mg/mL (781.91 mM)

Bioactivity

• In Vitro:
  The hepatic level of free Adrenic Acid (22:4n6) is markedly higher in the CDAHFD-fed db/db mice than in the SD-fed db/db mice. In plasma, the difference in the adrenic acid level reaches statistical significance (p<0.001). The hepatic and plasma levels of Adrenic Acid exhibit greater differences between the CDAHFD-fed db/db mice and the SD-fed db/db mice (8.6-fold higher vs. 1.6-fold higher in liver tissue, 5.3-fold higher vs. 2.2-fold higher in plasma) than those of well-known proinflammatory PUFA, such as Arachidonic Acid.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cis-7,10,13,16-Docosatetraenoic acid, Adrenic Acid, Inhibitor, Human Endogenous Metabolite, fatty, EndogenousMetabolite, Endogenous Metabolite, inhibit, inflammation, vascular, polyunsaturated

Compound Identifiers

PubChem CID

5497181