Adoprazine

SKU: orb1710486

Description

Adoprazine (SLV313) is a dual-action investigational compound, functioning as a dopamine D2 receptor antagonist and a serotonin 5-HT1A receptor agonist. It has been utilized in preclinical in vitro and in vivo studies to explore potential atypical antipsychotic mechanisms for psychiatric research.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 222551-17-9
• MW: 405.46
• Purity: 99.83%
• Formula: C₂₄H₂₄FN₃O₂
• SMILES: Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2cccc3OCCOc23)c1
• Target: 5-HT Receptor,Dopamine Receptor,Others
• Solubility: DMSO:45 mg/mL (110.99 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (6.17 mM)

Bioactivity

• Target IC50:
  D4 Receptor:8.0 (pKi)|D3 receptor:8.4 (pKi)|D3 receptor:8.9 (pA2)|5-HT1A receptor:9.1 (pKi)|5-HT1A receptor:9 (pEC50)|5-HT7 receptor:7.2 (pKi)|D2 Receptor:9.3 (pA2)|D2 Receptor:8.4 (pKi)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SLV 313, SLV313, SLV-313, Adoprazine

Compound Identifiers

PubChem CID

9887537