Adiphenine hydrochloride

SKU: orb1310969

Description

Adiphenine hydrochloride is a nicotinic acetylcholine receptor antagonist utilized as an antispasmodic agent. It is employed in pharmacological research to investigate cholinergic signaling and smooth muscle contraction in both in vitro and ex vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 50-42-0
• MW: 347.88
• Purity: 99.76% (May vary between batches)
• Formula: C₂₀H₂₅NO₂·HCl
• SMILES: O=C(OCCN(CC)CC)C(C1=CC=CC=C1)C2=CC=CC=C2.[H]Cl
• Target: AChR
• Solubility: H2O:64 mg/mL (183.97 mM);DMSO:50 mg/mL (143.73 mM);Ethanol:15 mg/mL (43.12 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (7.19 mM)

Bioactivity

• Target IC50:
  α1 nAChR:1.9 µM (IC50)|α4β2 nAChR:3.7 µM (IC50)|α4β4 nAChR:6.3 µM (IC50)|α3β4 nAChR:1.8 µM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Sentiv, Spasnil, inhibit, local, nicotinic, Nicotinic acetylcholine receptors, Nicotinic Receptor, Patrovina, nAChR, Inhibitor, anesthetic, Adiphenine, Adiphenine HCl, Adiphenine hydrochloride, Adiphenine Hydrochloride, acetylcholine

Compound Identifiers

PubChem CID

5763