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ADAR1i-124

SKU: orb3210276

Description

ADAR1i-124 is an A-to-I RNA editing inhibitor that suppresses the catalytic activities of ADAR1p150 and ADAR1p110. It activates Type I interferon (IFN) and ZBP1 pathways and inhibits the viability of various cancer cell lines in a dose-dependent manner. Additionally, ADAR1i-124 induces apoptosis and necroptosis, making it useful for cancer research, including studies on skin melanoma and ovarian cancer.

Images & Validation

Key Properties

TargetDNA/RNA Synthesis,Necroptosis,IFNAR,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information