AD186

SKU: orb2278309

Description

AD186 is a potent and selective sigma-1 receptor (S1R) agonist with high affinity (Ki = 2.7 nM) and 10-fold selectivity over the sigma-2 receptor. It serves as a valuable pharmacological tool for investigating S1R function in neuropathic pain models, as evidenced by its ability to reverse the antiallodynic effects of BD-1063 in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 320.47
• Formula: C₂₂H₂₈N₂
• Target: Sigma receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Sigma receptor