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Catalog Number | orb1146695 |
---|---|
Category | Small Molecules |
Description | Lipid A9 is an ionizable cationic lipid (pKa?= 6.27) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA and siRNA?in vivo.?LNPs containing lipid A9 and encapsulating non-stimulatory siRNA increase plasma levels of chemokine (C-C motif) ligand 2 (CCL2), indicating activation of the innate immune response, and decrease body weight in mice. |
MW | 905.51 |
CAS Number | [2036272-50-9] |
Formula | C57H112N2O5 |
SMILES | CCCCCCCCC(=O)N(CCCN(C)C)C(CCCCCCCCC(=O)OCC(CCCC)CCCCCC)CCCCCCCCC(=O)OCC(CCCC)CCCCCC |
Hazard Information | Non-Toxic |
Note | For research use only |
Chemical structure of orb1146695