Acuitas Lipid A9

SKU: orb1146695

Description

Lipid A9 is an ionizable cationic lipid (pKa = 6.27) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA and siRNA in vivo. LNPs containing lipid A9 and encapsulating non-stimulatory siRNA increase plasma levels of chemokine (C-C motif) ligand 2 (CCL2), indicating activation of the innate immune response, and decrease body weight in mice.

Key Properties

• CAS Number: 2036272-50-9
• MW: 905.51
• Purity: >95%
• Formula: C₅₇H₁₁₂N₂O₅
• SMILES: CCCCCCCCC(=O)N(CCCN(C)C)C(CCCCCCCCC(=O)OCC(CCCC)CCCCCC)CCCCCCCCC(=O)OCC(CCCC)CCCCCC

Storage & Handling

• Hazard Information: Non-Toxic
• Disclaimer: For research use only

Chemical structure of orb1146695