Actinonin

SKU: orb1089764

Description

Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities.

Key Properties

• CAS Number: 13434-13-4
• MW: 385.4983
• Purity: >98%
• Formula: C₁₉H₃₅N₃O₅
• SMILES: CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1C(CO)CCC1

Storage & Handling

• Disclaimer: For research use only