ACSS2-IN-2

SKU: orb1689837

Description

ACSS2-IN-2 (MTB-9655) is a potent and selective ACSS2 inhibitor with an IC50 of 3.8 nM. It serves as a valuable chemical probe for investigating the role of ACSS2 in research areas including cancer metabolism, viral pathogenesis, and neuropsychiatric disorders, as evidenced by in vitro and in vivo studies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2332820-04-7
• MW: 415.39
• Purity: 99.54% (May vary between batches)
• Formula: C₂₁H₁₉F₂N₃O₄
• SMILES: COC(=O)c1cccc(c1)N1N=C(C)C(C(=O)Nc2cccc(c2)C(C)(F)F)C1=O
• Target: Others,Fatty Acid Synthase
• Solubility: DMSO:150 mg/mL (361.11 mM)

Bioactivity

• In Vitro:
  ACSS2-IN-2 (Compound 261) (5 h) exhibits ACSS2 inhibitory activity with an IC50 of 3.8 nM in MDA-MB-468 cells.'

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ACSS2, ACSS2-IN-2, MTB 9655, MTB9655, MTB-9655, Fatty Acid Synthase, FattyAcidSynthase

Compound Identifiers

PubChem CID

139443008