AcrB-IN-6

SKU: orb3172878

Description

AcrB-IN-6 is an effective inhibitor of AcrB and suppresses the function of bacterial multidrug efflux pumps. AcrB-IN-6 significantly enhances the antibacterial activity of multiple antibiotics and produces 32-fold reductions in minimum inhibitory concentration (MIC) values in wild-type Escherichia coli BW25113. AcrB-IN-6 exhibits strong synergistic antibacterial effects together with low cytotoxicity and hemolytic properties. AcrB-IN-6 is utilized in research focused on antimicrobial resistance mechanisms, bacterial efflux systems, and strategies designed to restore antibiotic susceptibility in multidrug-resistant bacterial strains.

Key Properties

• CAS Number: 3082621-32-4
• MW: 509.48
• Purity: 99.40% (May vary between batches)
• Formula: C₂₈H₃₃BrN₂O₂
• SMILES: O=C(N1CCCCC1)CN2C=3C=C(OCC4=CC=C(Br)C=C4)C=CC3C5=C2CCC(C)(C)C5
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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