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    Acotiamide monohydrochloride trihydrate

    Acotiamide monohydrochloride trihydrate

    Catalog Number: orb1305701

    DispatchUsually dispatched within 3-5 working days
    $ 203.00
    Catalog Numberorb1305701
    CategorySmall Molecules
    DescriptionAcotiamide monohydrochloride trihydrate
    CAS Number773092-05-0
    Purity99.48%
    MW541.06
    SMILESs1c(nc(c1)C(=O)NCCN(C(C)C)C(C)C)NC(=O)c1c(cc(c(c1)OC)OC)O.O.Cl.O.O
    FormulaC21H37ClN4O8S
    Biological ActivityAcotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent appears to inhibit acetylcholinesterase (AchE), an enzyme responsible for the breakdown of acetylcholine (Ach). Increased Ach concentrations lead to an improvement of gastric emptying and GI motility and eventually to a reduction of dyspepsia symptoms.
    NoteFor research use only
    Expiration Date12 months from date of receipt.
    • Acotiamide HCl [orb315372]

      [773092-05-0]

      541.06

      C21H37ClN4O8S

      100 mg, 250 mg, 1 g, 10 mM * 1 mL in DMSO
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