AChE/GSK-3β-IN-1

SKU: orb1685897

Description

AChE/GSK-3β-IN-1 is a potent, brain-penetrant dual inhibitor of acetylcholinesterase (IC50: 1.2 nM) and glycogen synthase kinase-3β (IC50: 22.4 nM). It demonstrates selectivity within the CMGC kinase family, reduces oxidative stress by inhibiting ROS, and is a valuable research tool for investigating Alzheimer's disease pathology in cellular and animal models.

Research Area

Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2412364-73-7
• MW: 585.72
• Formula: C₃₁H₃₅N₇O₃S
• SMILES: N(CCNCC(NC1=CC(=CC=N1)C2=NC(OCC3CC3)=C(C(NC)=O)S2)=O)C4=C5C(=NC=6C4=CC=CC6)CCCC5
• Target: ROS Kinase,Others,Microtubule Associated,GSK-3,Cholinesterase (ChE)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162669319