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AChE/BChE-IN-23

SKU: orb2802178

Description

AChE/BChE-IN-23 is a dual cholinesterase inhibitor with antioxidant and anti-neuroinflammatory properties. It inhibits Aβ and Tau aggregation in vitro and reduces NLRP3 inflammasome in microglia, while also reversing scopolamine-induced memory deficits in mouse models of cognitive impairment.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Signal Transduction

Images & Validation

Key Properties

MW367.4
FormulaC19H21N5O3
SMILESN/C(C1=CC=CC(NC(NCCC2=CNC3=C2C=C(OC)C=C3)=O)=C1)=N/O
TargetBeta Amyloid,Mitochondrial Metabolism,Parasite,Microtubule Associated,ROS,Reactive Oxygen Species,Cholinesterase (ChE),NOD-like Receptor (NLR),Cytochromes P450

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

AChE/BChE-IN-23 (orb2802178)

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