AChE-IN-105

SKU: orb3174930

Description

AChE-IN-105 (Compound C5) is a potent mixed-type AChE inhibitor with an IC50 value of 5.02 μM. It effectively scavenges ROS, reduces hydrogen peroxide-induced Caspase-3 activation, and inhibits the Nrf2-ARE pathway. In a Scopolamine-induced zebrafish cognitive impairment model, AChE-IN-105 prevents memory deficits and demonstrates strong antioxidant activity. It is applicable in Alzheimer's disease research.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Protein Biochemistry

Key Properties

• CAS Number: 2678601-07-3
• MW: 478.45
• Formula: C₂₆H₂₂O₉
• SMILES: [C@@H](CC(OC)=O)(C1=C2C(C(=O)C=C(O2)C3=CC=CC=C3)=C(O)C(O)=C1O)C4=CC(O)=C(OC)C=C4
• Target: Caspase,Nrf2,ROS,Cholinesterase (ChE)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase,Nrf2,ROS,Cholinesterase (ChE)