Acevaltrate

SKU: orb1297691

Description

Acevaltrate is a cytotoxic small molecule with in vitro activity against human small-cell lung cancer (GLC4) and colorectal cancer (COLO 320) cell lines, exhibiting IC50 values in the 1-6 µM range. It is a research tool for studying anticancer mechanisms and valepotriate derivatives in oncology.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 25161-41-5
• MW: 480.50
• Purity: 99.94% (May vary between batches)
• Formula: C₂₄H₃₂O₁₀
• SMILES: [H][C@]12[C@H](OC(=O)CC(C)C)OC=C(COC(C)=O)C1=C[C@H](OC(=O)CC(C)(C)OC(C)=O)[C@]21CO1
• Target: ATPase
• Solubility: 10% DMSO+90% Corn Oil:3.30 mg/mL (6.87 mM);DMSO:125.00 mg/mL (260.15 mM)

Bioactivity

• Target IC50:
  COLO 320 cells:1-6 μM|GLC4 cells:1-6 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Acevaltrate, Acevaltratum, Acetoxyvaltrate, Inhibitor, inhibit, Na+/K+ ATPase, Sodium potassium pump

Compound Identifiers

PubChem CID

65717