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Acetylshikonin

SKU: orb1301243

Description

Acetylshikonin is a bioactive shikonin derivative that exhibits antiangiogenic and antitumor effects by inhibiting cell proliferation and NADPH oxidase assembly. It induces apoptosis in cancer cells via endoplasmic reticulum stress and Nur77 pathway modulation, while also demonstrating anti-inflammatory activity by suppressing mast cell degranulation in vivo.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Neuroscience

Images & Validation

Key Properties

CAS Number24502-78-1
MW330.33
Purity99.74% (May vary between batches)
FormulaC18H18O6
SMILESCC(C)=CC[C@@H](OC(C)=O)C1=CC(=O)c2c(O)ccc(O)c2C1=O
TargetAutophagy,Antibacterial,Cholinesterase (ChE),Apoptosis,Cytochromes P450
SolubilityDMSO:3.31 mg/mL (10.02 mM)

Bioactivity

Target IC50
CYP450:1.4-4.0 μM (IC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CYPs, Cytochrome P450, Cholinesterase (ChE), Acetylshikonin, AChE, Acetyl shikonin, Inhibitor, inhibit

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 180.00
25 mg
$ 310.00
50 mg
$ 440.00
100 mg
$ 630.00
500 mg
$ 1,320.00
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