Acetyl-trans-resveratrol

SKU: orb1220821

Description

Acetyl-trans-resveratrol has anti-cancer activityit inhibits the phosphorylation of STAT3 and NFκB down-regulates Mcl-1 and up-regulates Bim and Puma in pancreatic cancer cells.

Key Properties

• CAS Number: 42206-94-0
• MW: 354.35
• Purity: >98% (HPLC)
• Formula: C₂₀H₁₈O₆
• SMILES: CC(=O)Oc1ccc(cc1)\C=C\c1cc(OC(C)=O)cc(OC(C)=O)c1
• Target: STAT
• Solubility: DMSO:50mg/m(141.24 mM)

Bioactivity

• In Vitro:
  Triacetylresveratrol significantly down-regulates anti-apoptotic Bcl-2 family protein Mcl-1 and up-regulates pro-apoptotic Bcl-2 family proteins Bim and Puma. Triacetylresveratrol inhibits cell viability, and induces apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

STAT