Acetyl-CoA Carboxylase-IN-1

SKU: orb1745079

Description

ACC-IN-1 is a potent and selective acetyl-CoA carboxylase (ACC) inhibitor with demonstrated antibacterial activity. Its application extends to research on metabolic disorders, including studies in cellular models and animal systems to investigate lipid metabolism and related diseases.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 179343-23-8
• MW: 395.05
• Formula: C₁₃H₉Br₂N₅
• SMILES: BrC1=C(C(Br)=CC=C1)C2=CC3=C(N=C2N)N=C(N)N=C3
• Target: Others
• Solubility: DMSO:30 mg/mL (75.94 mM)

Bioactivity

• In Vitro:
  Acetyl-CoA Carboxylase-IN-1 (0.012-25 μM) exhibits antibacterial activity in Escherichia coli with MIC values ​​of >25, 3.13, 25, 0.39, 1.56, and 0.1 μM for WT, WT+ PMBN, ΔacrAB, ΔacrAB+PMBN, ΔtolC, and ΔtolC+ PMBN, respectively.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ACC-IN-1

Compound Identifiers

PubChem CID

5328120