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AcdK

SKU: orb3211215

Description

AcdK is a non-natural amino acid and a precursor of allysine. It can be site-specifically incorporated into target proteins in Escherichia coli using an amber codon suppression strategy. AcdK enables site-specific lysine dimethylation or monomethylation modifications of target proteins. It can synthesize site-specific lysine-methylated variants of histone H3 and p53, which are useful for studying the substrate specificity and catalytic functions of epigenetic enzymes.

Images & Validation

Key Properties

CAS Number2097535-26-5
MW319.32
FormulaC14H17N5O4
SMILESC(OC(NC=CCC[C@@H](C(O)=O)N)=O)C1=CC=C(N=[N+]=[N-])C=C1
TargetAmino Acids and Derivatives

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information