Acalabrutinib enantiomer

SKU: orb1741378

Description

Acalabrutinib enantiomer

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1952316-43-6
• MW: 465.51
• Purity: 99.20%
• Formula: C₂₆H₂₃N₇O₂
• SMILES: CC#CC(=O)N1CCC[C@@H]1c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12
• Target: BTK
• Solubility: DMSO:12 mg/mL (25.78 mM)

Bioactivity

• In Vitro:
  The compound has been shown to induce apoptosis (programmed cell death) in cancer cells and to inhibit the proliferation and migration of cancer cells. Acalabrutinib enantiomer has also been shown to have immunomodulatory effects, enhancing the activity of immune cells such as T cells and natural killer cells .

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Acalabrutinib enantiomer, BTK, R-Acalabrutinib

Compound Identifiers

PubChem CID

121413436